Search results for "Conrotatory and disrotatory"

showing 3 items of 3 documents

On the mechanism of catalytic isomerization of xylenes. Molecular orbital studies

1979

Abstract On the basis of CNDO/2 molecular orbital calculations, we postulate the following detailed mechanism for the catalytic isomerization of xylenes which explains the initial product distributions and also our previous finding that the reaction is intramolecular: (i) adsorption of xylene on a surface acid site to form a Wheland-type complex; (ii) disrotatory cyclization of the protonated species into a bicyclo[3, 1, 0]hexenyl complex; (iii) migration of the methylene bridge to a new side of the pentagonal ring; (iv) change of the new bicyclic species back into the corresponding Wheland-type complex; (v) desorption of the xylene isomer from the surface of the catalyst. The overall rate …

Bicyclic moleculeChemistryXyleneProtonationRate-determining stepPhotochemistryMedicinal chemistryCatalysisCNDO/2chemistry.chemical_compoundMolecular orbitalPhysical and Theoretical ChemistryConrotatory and disrotatoryIsomerizationJournal of Catalysis
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Unravelling the mechanism of the ketene-imine Staudinger reaction. An ELF quantum topological analysis

2015

The mechanism of the ketene-imine Staudinger (KI-S) reaction between t-butyl-cyano ketene and N-phenyl phenylimine has been studied using DFT methods at the MPWB1K/6-311G(d) computational level. The reaction takes place through a two-step mechanism: (i) the first step is the nucleophilic attack of the imine nitrogen lone pair on the central carbon of the ketene yielding a zwitterionic (ZW) intermediate; (ii) the second step, which is the rate- and stereoselectivity-determining step, is a ring-closure process achieved by a nucleophilic attack of the terminal carbon atom of the ketene on the imine carbon atom. Due to the unfeasibility of a cis/trans and an E/Z stereoisomerisation at the ZW in…

ChemistryStereochemistryGeneral Chemical EngineeringImineKeteneGeneral ChemistryTopologychemistry.chemical_compoundNucleophileSingle bondStaudinger reactionConrotatory and disrotatoryHOMO/LUMOLone pairRSC Advances
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The electronic substituent influence on the thermally allowed electrocyclic interconversion cyclobutene/butadiene. A MNDO study

1984

The effects of donor/acceptor substitution on the conrotatory cyclobutene/butadiene interconversion have not yet been experimentally studied. MNDO Synchronous Transit/MINIMAX calculations for all possible combinations of NH2/NH3 + 3 groups at the fissile single bond reveal very large substituent effects on the opening reactions and reverse cyclisations. Diamino(1b/2b), diammonio-(1c/2c) and amino-ammonio-substitutions (1d/2d) change the activation energy of the reference ring opening reaction (1a →2a) from 49.9 kcal/mol to 34.7, 29.8 and 26.0 kcal/mol, respectively. This rate enhancement parallels the monotone shift of the transition state pathcoordinate towards the cyclobutenes. Relative t…

Hammond's postulateElectrocyclic reactionCyclobuteneSubstituentMNDOPhotochemistrychemistry.chemical_compoundchemistryComputational chemistryElectronic effectSingle bondChiropracticsPhysical and Theoretical ChemistryConrotatory and disrotatoryTheoretica Chimica Acta
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